Joseph Gordon-Levitt Replaces James McAvoy in Untitled Cancer Comedy

     March 2, 2010

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MTV reports that James McAvoy has unfortunately dropped out of Jonathan Levine’s (The Wackness) untitled cancer comedy co-starring Seth Rogen.  But in for McAvoy is the highly talented Joseph Gordon-Levitt.  McAvoy apparently had to bow out for personal reasons, which is a shame since when he spoke to Steve during the press junket for The Last Station, he seemed really excited about doing the film.  But anyone who’s familiar with Gordon-Levitt’s work can knows he’s up for handling the role and that he’s a strong addition to this cast, which also includes Bryce Dallas Howard and Oscar-nominee Anna Kendrick.

Originally titled I’m With Cancer, the film is based on the real-life experience of screenwriter Will Reiser and his diagnosis and battle with the disease during his 20s.

Hit the jump to read a statement from Rogen (who is also a producer on the film) on the change-up.

Here’s what Rogen had to say about the loss of McAvoy and the gain of Gordon-Levitt:

“It’s incredibly unfortunate that circumstances outside of everyone’s control have taken James away from the project, but, with James’s blessing, we were able to have Joseph step in to take on the [lead] role of Adam. We all look forward to working with James in the future.”

This is the film’s second change-up after Levine stepped in for Nicole Holofcener, who also had to drop out due to personal reasons.

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