Meg Ryan (The Women), Curtis "50 Cent" Jackson (Twelve), John Lithgow (Dexter), Joe Anderson (The Crazies), and Kat Dennings (Thor) assume the lead roles in the ensemble drama Lives of the Saints.  Kevin Zegers (Gossip Girl), Anthony Anderson (Law & Order), and Esai Morales (Caprica) also appear in the film, the feature debut of writer/director Chris Rossi.

According to Variety, the film tells "the intertwining stories of a group of Angelenos seeking redemption for past mistakes, only to find that forgiveness comes from unlikely places."  Like any logline that contains the phrase "comes from unlikely places," this one sounds terrible.  But the cast is mad eclectic.  That's got to be good for something.  For instance, a scene between John Lithgow and 50 Cent may achieve the greatest disparity in acting talent ever captured on film.  Filming begins November 13th.