Showtime has released the full trailer for its new drama series Masters of Sex.  The show stars Michael Sheen and Lizzy Caplan as William Masters and Virginia Johnson, real-life pioneers of the study of human sexuality whose work sparked the sexual revolution and catapulted them to fame.  This trailer shows a great deal of, well, sex, but the series also looks to delve pretty heavily into other issues like the importance of love with regards to sex, the idea of Masters’ research as smut vs. science, and of course complex character relationships.  The series also seems to have a good sense of humor as well, with Beau Bridges stealing a couple of scenes with his comedic work.

Hit the jump to watch the full trailer.  The series also stars Caitlin FitzgeraldNicholas D'Agosto, and Teddy Sears.  Masters of Sex debuts on Showtime Sunday, September 29th.

Here’s the official synopsis for Masters of Sex:

MASTERS OF SEX is a one-hour drama starring acclaimed actors Michael Sheen and Lizzy Caplan, who will portray the real-life pioneers of the science of human sexuality, William Masters and Virginia Johnson. The series chronicles the unusual lives, romance, and pop culture trajectory of Masters and Johnson. Their research touched off the sexual revolution and took them from a mid-western teaching hospital in St. Louis to the cover of Time magazine and nearly a dozen appearances on Johnny Carson’s couch. Caitlin Fitzgerald (It’s Complicated), Nicholas D’Agosto (Heroes), and Teddy Sears (American Horror Story) also star. Emmy and Golden Globe award-winning actor Beau Bridges and Emmy Award winner Margo Martindale also star. The series is an adaptation of Thomas Maier’s book Masters of Sex: The Life and Times of William Masters and Virginia Johnson, The Couple Who Taught America How to Love. The pilot was directed by Academy Award® nominee John Madden (Shakespeare in Love, The Best Exotic Marigold Hotel). Produced by Sony Pictures Television, Michelle Ashford (The Pacific) and Sarah Timberman and Carl Beverly (Justified, A Gifted Man) serve as executive producers.