Ryan Reynolds has been cast opposite Denzel Washington in the upcoming thriller Safe House.  As we reported last week, Reynolds was the front-runner on a short list of actors jockeying for the highly-contested role.  Other stars considered for the part included Sam Worthington, Shia LaBeouf, and Zac Efron.  Per Deadline, "The film centers on a young CIA agent (Reynolds) who must transport a dangerous criminal (Washington) to safety after both are attacked at a safe house."  Basically, it sounds like 3:10 to Yuma, but Vulture described it as Three Days of the Condor crossed with Collateral.  Daniel Espinosa will direct from a script by David Guggenheim.

Hit the jump for how Safe House is fitting in to Reynolds' busy schedule.

Reynolds recently wrapped filming on Green Lantern and is set to begin shooting in October on the comedy The Change-Up with Jason Bateman.  If Reynolds' deal for Safe House goes through, then he'll shoot that film in early 2011.  From there, it's unknown whether he'll do Deadpool or RIPD.  Deadline says Reynolds wants to make both so one will follow the other.  Reynolds is also going to be doing heavy promotion in the summer for Green Lantern, which comes out on June 17, 2011.