Though we have yet to see a trailer for the film, the first clip from The Guilt Trip has been released.  Written by Dan Fogelman (Crazy, Stupid, Love.), the comedy stars Seth Rogen as an inventor who sets out on a business trip with his mother (Barbra Streisand) in tow.  Unbeknownst to her, Rogen plans on reuniting his mother with a long lost love.  This clip features Rogen trying to convince his mother to accompany him on the 8-day road trip without giving away his true intentions.  There’s not really enough footage here to judge the comedic pairing of Rogen and Streisand, but the clip definitely shows promise.  Moreover, the supporting cast of Adam Scott, Yvonne Strahovski, Colin Hanks, and Danny Pudi is encouraging.

Hit the jump to watch the clip.  Directed by Anne Fletcher (The Proposal), the film also stars Dale Dickey and Kathy Najimy.  The Guilt Trip opens on Christmas Day.

Click over to Yahoo! to watch in HD.

Here’s a synopsis for The Guilt Trip:

Andy Brewster (Seth Rogen) is an inventor who lives in Los Angeles. He’s come up with an amazing organic cleaner but can’t get anyone interested in manufacturing it.

Andy plans a business trip to promote the product and decides to take his recently-widowed mother (Barbra Streisand) along for the ride. She’s been despondent since his father died, so he comes up with a great idea—during the trip he’ll surprise her with a stop in San Francisco, where one of her ex-flames lives.