In the mood for a series that takes you to new worlds and impossible destinations? Sounds like it's time for some sci-fi. Because when you need to get away, sometimes a little genre storytelling is just the ticket. After all, if you want to get away, you might as well go all the way to space. If you're looking for something streaming right now, we've got you covered with the best sci-fi TV shows on Prime Video. From superheroes to space sagas, whatever you're in the mood for, we've got a recommendation below.

Don't see what you're looking for here? Check out our list of the best shows on Prime Video, sci-fi shows on Netflix or Hulu, or the overall best sci-fi shows of the 21st century.

Disclaimer: These titles are available on US Prime Video.

'Upload' (2020 - Present)

Rotten Tomatoes: 92% | IMDB: 7.9/10

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Set in the near-future, technology has really ramped up. We now have even smaller phones, more daily conveniences, self-driving cars, oh, and we can now upload ourselves into a virtual afterlife, essentially becoming immortal. Upload follows Nathan (Robbie Amell) after his unexpected death and upload into the very expensive afterlife called Lakeview. Uploaded by his controlling girlfriend Ingrid (Allegra Edwards), he finds comfort in befriending his still-living customer service rep Nora (Andy Allo). Soon, inevitably, sparks fly between Nora and Nathan as they spend more time together in a virtual utopia. But problems arise in the real world where looming issues like large corporations taking over control and human rights violations are hitting far closer to home. Soon it becomes about more than just relationship problems between the alive and dead, and a fight for the future of humanity. All of that and more is wrapped up in the humor and romance of Upload. — Therese Lacson Watch on Prime Video

'Gen V' (2023 - Present)

Rotten Tomatoes: 97% | IMDb: 7.8/10

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A spinoff of the worldwide hit superhero series The Boys, Gen V centers on a group of first-generation superhero teenagers as their everyday adolescent lives come head-to-head with their superhuman abilities. The likes of Jaz Sinclair, Chance Perdomo, Lizze Broadway, and Maddie Phillips excel in the lead roles, perfectly blending action-packed drama with the sort of teen angst one could expect from a John Hughes movie. Packed full of narrative twists, Gen V takes the same tonal aspects that made The Boys such a success and welcomes in a new audience with its tackling of very real teenage social issues. - Jake Hodges Watch on Prime Video

'The Twilight Zone' (1959 - 1964)

Rotten Tomatoes: 92% | IMDb: 9.1/10

The Twilight Zone is one of the most influential television shows of all time. Created by Rod Serling in 1959, the anthology series utilized science fiction to present tales of morality and human nature, as well as social commentary on racism, war, and gender roles. It has spawned three revival series, a film, and a theme park attraction, not to mention it inspired series like Twin Peaks, The X-Files, and Black Mirror. Some episodes of the acclaimed series have directly inspired films across all genres, from Us to Toy Story 4, lending not only its trademark supernatural plot devices but also its dark take on human nature. - Jenna Gurka Watch on Prime Video

'Person of Interest' (2011 - 2016)

Rotten Tomatoes: 92% | IMDb: 8.5/10

Person of Interest is a science-fiction series inspired by a fascinating concept. Created by Jonathan Nolan, Person of Interest stars Michael Emerson (Saw) as Harold Finch, a reclusive billionaire and computer genius who creates a program that identifies people planning terrorist attacks. Similar in foundation premise to Minority Report, Person of Interest explores themes of privacy, as well as the conflicts between technology and morality. An espionage procedural series co-starring Jim Caviezel, Person of Interest attracted a wide audience resulting in five seasons of intriguing mysteries, as well as captivating characters .– Yael Tygiel Watch on Prime Video

'I’m a Virgo' (2023)

Rotten Tomatoes: 96% | IMDb: 7.1/10

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Director and series creator Boots Riley (Sorry to Bother You) uses his signature surrealist style to produce a modern folktale set in Oakland, CA. I’m a Virgo follows Cootie (Jharrel Jerome), a 13-foot-tall Black teen who finally ventures outside the confines of his adoptive parents’ home to find a world that is eager to embrace, exploit, and possibly eradicate him. The series literalizes some of the struggles that Black teens face in a society that projects so many things onto them even though they just want to be normal kids. Riley creates a visually unique and stunning coming-of-age story that feels just as grounded as it does magical. – Tauri Miller Watch on Prime Video

'Dead Ringers' (2023)

Rotten Tomatoes: 85% | IMDb: 6.5/10

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Rachel Weisz (Black Widow) is absolutely magnetic in a deeply disturbing reimagining of David Cronenberg’s 1988 film Dead Ringers. An unhinged horror series, Dead Ringers captivates with Weisz in the lead, playing twins Elliot and Beverly Mantle alongside a stellar supporting cast that includes Emily Meade (The Leftovers), Jennifer Ehle (She Said), and Michael Chernus (Orange is the New Black). Through vivid, graphic imagery, spine-tingling suspense, and an intriguing plot, Dead Ringers is six episodes of unsettling twists and turns baked into a gripping mystery and undeniably stylish visual aesthetic. – Yael Tygiel Watch on Prime Video

'The Power' (2023)

Rotten Tomatoes: 74% | IMDb: 6.6/10

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Toni Collette stars in The Power as the mayor of Seattle, who is forced to handle an inexplicable situation where teenage girls around the world suddenly and mysteriously develop electrical powers. Adapted from Naomi Alderman’s clever book by Sarah Quintrell and Claire Wilson, The Power is a fascinatingly refreshing approach to the currently oversaturated superhero genre. Built on a foundation of reality, specifically from the perspective of young women, The Power deliberately explores imbalances of sex and class. Through carefully crafted intertwining stories, The Power features incredible performances from Collette and Auli'i Cravalho (Moana), along with co-stars Toheeb Jimoh from Ted Lasso and John Leguizamo. – Yael Tygiel Watch on Prime Video

'Fringe' (2008 - 2013)

Rotten Tomatoes: 90% | IMDb: 8.4/10

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Fringe is a highly underrated series with deep and complex worldbuilding containing layers upon layers of lore. Initially an episodic scientific monstrosity of the week sci-fi drama like its spiritual predecessor, The X-Files, the series quickly spins out into a serialized character-driven ensemble show following the FBI’s secret Fringe Division. Agent Olivia Dunham (Anna Torv) is assigned to investigate a wave of unexplained occurrences that all deal with elements of fringe science known as “The Pattern.” Unfortunately, she is forced to enlist the help of institutionalized scientist Walter Bishop (John Noble) and his con artist son Peter Bishop (Joshua Jackson). Fringe is one of the best sci-fi series of the last decade that gets better with every rewatch. – Tauri Miller Watch on Prime Video

'The Rig' (2023 - Present)

Rotten Tomatoes: 67% | IMDb: 5.8/10

Emily Hampshire (Schitt’s Creek) and Iain Glen (Game of Thrones) star in a brand-new drama called The Rig from newcomer David Macpherson. The Rig is a tense series that blurs the line between science fiction thriller and workplace drama, as it follows a stranded oil rig crew cut off from help while off the coast of Scotland in the North Sea. Supporting Hampshire and Glen are Martin Compston and Mark Bonnar, heating up the interpersonal tensions through The Rig’s survival story, which is emphasized by the dangerous environment of oil rigs, along with the threats arising from man’s interference with nature. – Yael Tygiel Watch on Prime Video

'Three Pines' (2022)

Rotten Tomatoes: 72% | IMDb: 7.2/10

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Created by Emilia di Girolamo and based on Louise Penny’s novel series, Three Pines follows Chief Inspector Armand Gamache of the Sûreté du Québec police force, played stoically by Alfred Molina (Spider-man: No Way Home). Di Girolamo’s choice to spread four murder mysteries in the small idyllic town across two episodes each allows the Chief Inspector to both uncover the truths of the crimes as well as truths about himself. Although featuring Rossif Sutherland (Reign) and Elle-Máijá Tailfeathers, Three Pines leans heavily on Molina’s detective, whose uncanny perception reveals what others cannot see in the shadows of crime. Critically acclaimed and compared favorably to Agatha Christie and Columbo, Three Pines is an unexpected Canadian-based hit. – Yael Tygiel Watch on Prime Video

'Grimm' (2011 - 2017)

Rotten Tomatoes: 89% | IMDb: 7.9/10

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Grimm began its six seasons as a procedural monster-of-the-week type show centered around homicide detective Nick Burkhardt (David Giuntoli), who discovers his familial lineage of monster hunters who protect humanity from the monsters who walk among them. Truly an underrated gem, Grimm served as a launchpad for stars like Bitsie Tulloch, who currently dominates on Superman and Lois, as well as The L Word: Generation Q’s Jacqueline Toboni. Over the course of the series, Grimm evolved into a fun and creative ensemble with an incredibly complex and rich mythology. Creators Stephen Carpenter, David Greenwalt, and Jim Kouf cultivated a series that progressed with their audience, letting Grimm lean into what worked without compromising quality, engrossing storytelling. – Yael Tygiel Watch on Prime Video

'The Peripheral' (2022)

Rotten Tomatoes: 79% | IMDb: 7.6/10

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Chloë Grace Moretz stars in The Peripheral, a lofty science-fiction thriller set in the not-too-distant future where society has become manipulated by technology. With a mysterious premise that forces viewers to question everything, The Peripheral explores the idea that virtual reality systems may actually be windows to alternate timelines or even our future. Centrally placed in a gripping puzzle, Moretz’s Flynne flows through realities, approaching fascinating questions about time, destiny, and truth. Created by Scott Smith and based on William Gibson’s novel, The Peripheral is a mind-bending series with a great cast wrapped up in a riveting adventure. – Yael Tygiel Watch on Prime Video

'American Horror Story' (2011 - Present)

Rotten Tomatoes: 77% | IMDb: 8.0/10

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A horror show from the creators of Glee and Pose? Yup, you heard us right. Ryan Murphy and Brad Falchuk offer up a plethora of scares in anthology series American Horror Story. In its decade-long run, the show has covered everything from a haunted house to a creepy hotel, a coven to a cult. It’s served up countless screams and memes alike and featured some memorable performances from Lady Gaga in one of her first acting roles and veterans Sarah Paulson and Jessica Lange. – Taylor Gates Watch on Prime Video

'Paper Girls' (2022)

Rotten Tomatoes: 87% | IMDb: 7.3/10

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Finished Stranger Things but are still craving some 80s nostalgia? Add Paper Girls to your watchlist! Based on the comic book series by Brian K. Vaughan, the show follows four very different girls — super-smart Tiff (Camryn Jones), new girl Erin (Riley Lai Nelet), tomboy Mac (Sofia Rosinsky), and well-off KJ (Fina Strazza) – as they get caught in a war of time travelers and must band together to save the world. As they meet their future selves, questions about destiny pop up, and they must decide whether to accept or fight against their fate. The show has been praised for the performances of its young talent and sharp writing. – Taylor Gates Watch on Prime Video

'Undone' (2019 - 2022)

Rotten Tomatoes: 97% | IMDb: 8.2/10

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Undone is a unique show for a myriad of reasons, the first of which is its visuals. The show employs a technique called rotoscoping, which uses live-action footage as a basis for its animation style. This allows the show to look more fluid and realistic than even the best CGI. The second of which is its plot. The show centers around Alma Winograd-Diaz (Rosa Salazar), a woman who’s bored with her life. After she survives a car accident than nearly kills her, however, things get a lot more interesting, as her relationship with time and reality is changed, allowing her to find out the truth of her father’s death. With excellent performances, breathtaking effects, and a fascinating plot, Undone is an underrated gem you don’t want to miss. – Taylor Gates Watch on Prime Video

'Utopia' (2020)

Rotten Tomatoes: 50% | IMDb: 6.7/10

Adapted from a British program of the same name by Gillian Flynn, the mastermind behind Gone Girl and Sharp Objects, Utopia explores what happens when a group of online friends find a cult underground comic book – and shortly after become tasked with saving the world. The show explores themes of a deadly virus and eugenics, and those subjects, combined with the violent nature of the show, sometimes make for a difficult watch. However, fans of gritty shows like The Boys or Hunters are sure to be intrigued. – Taylor Gates Watch on Prime Video

'Solos' (2021)

Rotten Tomatoes: 44% | IMDb: 6.0/10

Solos is an anthology series that tells seven different stories with a common theme: what it means to be human. The show has a fascinating thesis exploring the fact that, even when we feel our most isolated, we are connected to many different people due to our shared experience of living. There is a broad range of sci-fi staples explored throughout the episodes, from space to new technology. The acting in the show has been lauded, particularly Anne Hathaway’s depiction of a scientist attempting to time travel and Anthony Mackie’s performance as angry businessman Tom. – Taylor Gates Watch on Prime Video

'Tales from the Loop' (2020)

Rotten Tomatoes: 86% | IMDb: 7.4/10

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Nominated for two Emmys in 2020, Tales from the Loop follows a group of people in Ohio who live above an underground facility called the Mercer Center for Experimental Physics, where there’s a machine created to unlock and explore the world’s most intriguing mysteries. The shows acts as an anthology series in a way, as it follows various interconnected people affected by the Loop. Though the pace can be slow at times, Tales from the Loop is an intriguing surrealist watch. – Taylor Gates Watch on Prime Video

'Outer Range' (2022 - Present)

Rotten Tomatoes: 79% | IMDb: 7.1/10

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Ever wonder what would happen if someone smashed a VHS tape of an old sci-fi film together with one of your dad’s favorite Westerns? Well, if you were thinking Cowboys vs. Aliens, you’d be wrong. No, the result is Outer Range, Prime Video’s science-fiction neo-Western series that premiered in early 2022 and continues to leave audiences buzzing. Starring Josh Brolin as rancher and patriarch Royal Abbott, the series follows residents of a small town in Wyoming as strange happenings begin to complicate their daily lives, including the appearance of a massive, bottomless hole on the Abbotts’ west pasture. Even stranger is the appearance of a young woman (Imogen Poots), who seems to have answers about Royal’s life that even he doesn’t possess. The series is a slow-burn, surely, but boasts one of the best ensemble cast in Prime Video’s history, including standouts Tamara Podemski as Deputy Sheriff Joy Hawk, the only sense of real authority in tiny Wabang, and Lewis Pullman as Rhett Abbott, the down-on-his-luck, bull-riding youngest son of Royal and his wife Cecelia (Lili Taylor). The desire for answers about the hole in the Abbott’s land makes the series perfect binge material, meshing together two of Hollywood’s most celebrated genres for something entirely unique. —Maggie Boccella Watch on Prime Video

'Lost' (2004 - 2010)

Rotten Tomatoes: 86% | IMDb: 8.3/10

If you were alive in the early 21st century, you probably remember the Lost fanfare – and the subsequent blowback. The addictive sci-fi mystery series kept its loyal fans guessing each week as to what the true role of the island was, who among the sprawling cast would make it, and what further secrets were in store. Whether or not Lost ended up justifying all of its mystery boxes is still up for debate, but it's hard to not get addicted. If you watched Lost just for the plot, you may have been let down. If you simply loved the characters, then it wrapped up perfectly. – Liam Gaughan Watch on Prime Video