One of the two Cabin Fever prequels is almost ready to shoot, as director Kaare Andrews (Altitude) is in final talks to helm the project. The first prequel, Cabin Fever: Patient Zero will trace the roots of the deadly virus witnessed in the 2002 original directed by Eli Roth. The plot will follow passengers aboard a cruise ship in the Caribbean as they deal with an outbreak of the virus following a collision with an abandoned research vessel. Andrews will direct from a screenplay by Jake Wade Wall (The Hitcher) and filming will take place in the Dominican Republic. Hit the jump for more.Heat Vision reported on Andrews directing Cabin Fever: Patient Zero. Best known for his work in the world of comics, Andrews grew up shooting Super 8 films, much like Cabin Fever-director, Roth. Andrews has previously worked on Marvel Comics’ “The Incredible Hulk,” “Ultimate X-Men” and “Spider-Man: Reign,” and is currently drawing up covers for the Ultimate line. His feature debut was the high-flying horror movie, Altitude released in 2010 by Anchor Bay. Currently, he has an entry in alphabetical horror anthology, ABC’s of Death; his entry is entitled, V is for Vagitus.Cabin Fever: Patient Zero is expected to pave the way for the second prequel, Cabin Fever: Outbreak. That story, written by Adam and Deborah Marcus (Leatherface 3D), tells the story of a doctor and his family who investigate a flu outbreak on a Caribbean island. Not surprisingly, they encounter the flesh-eating virus and are tasked with preventing a global epidemic. Though the prequels are expected to shoot back-to-back, there are no reports yet as to whether or not Andrews is attached for both films.