While we recently got news that another one of Fox’s “Animation Domination” shows is vacating the network (American Dad is moving to TBS in 2014), it appears that Fox’s two most popular animated series are planning the crossover episode to end all crossover episodes.  Fox has announced that The Simpsons will pay a visit to the Griffin household in a very special episode of Family Guy next fall.  Here's how Fox describes the episode, titled "The Simpsons Guy":

Peter (Seth MacFarlane) and the Griffins get out of dodge and end up in Springfield, where they are greeted by a friendly stranger named Homer Simpson (guest voice Dan Castellaneta), who welcomes his new “albino” friends with open arms. The families get along famously: Stewie (MacFarlane) becomes obsessed with Bart (guest voice Nancy Cartwright) and his old-fashioned pranks; Lisa (guest voice Yeardley Smith) takes Meg (Mila Kunis) under her wing and is determined to find something – anything – at which she excels; Marge (guest voice Julie Kavner) and Lois (Alex Borstein) ditch housework for a little bonding; and Peter and Homer fight over the best beer in town – Pawtucket vs Duff.

Audiences have been wondering for some time when/if the two pop culture juggernauts would meet, and it looks like that time will finally be Fall 2014.  It'll be interesting to see how the comedic sensibilities of both shows will mesh, and I'm looking forward to seeing the bonding between Peter and Homer materialize.