Are George Clooney and Angelina Jolie going to play two of America's biggest icons?  They are if author Andrew O'Hagan is to be believed.  At this weekend's Edinburgh International Book Festival, O'Hagan said [via The Playlist] that an adaptation of his book The Life and Opinions of Maf the Dog, and of His Friend Marilyn Monroe with Clooney as Frank Sinatra and Jolie as Monroe.  He added that production was set to begin shortly.However, this sounds a bit like fantasy casting.  It would definitely be a powerful one-two punch of acting talent, but we're going to wait for a second source to come out on this one.  Hit the jump for what Clooney and Jolie have on their schedules as well as a synopsis for Maf the Dog.angelina_jolie_red_dress_image_01Clooney, who will next be seen in theaters on September 1st with The American, is in Alexander Payne's next movie, The Descendants.  Also, last November we reported that Clooney was planning to direct Hamdan v. Rumsfeld in 2011 with Matt Damon to star.As for Jolie, she's been linked to numerous projects:  the title roles in Cleopatra: A Life, Tim Burton's Maleficent, and untitled Kay Scarpetta project (based off the books by Patricia Cornwall), and the thriller Serena directed by Darren Aronofsky.  However, speaking to MTV, Jolie made it sound like all of these projects are in very early development.  And as we reported on Friday, Salt 2 may also be in the works. Jolie will next be seen alongside Johnny Depp in Florian Henckel von Donnersmarck's The Tourist.Here's the synopsis for The Life and Opinions of Maf the Dog, and of His Friend Marilyn Monroe:

In November 1960, Frank Sinatra gave Marilyn Monroe a dog. His name was Maf. He had an instinct for the twentieth century. For politics. For psychoanalysis. For literature. For interior decoration. This is his story.

Maf the dog was with Marilyn for the last two years of her life. Not only a picaresque hero himself, he was also a scholar of the adventuring rogue in literature and art, witnessing the rise of America's new liberalism, civil rights, the space race, the New York critics, and was Marilyn Monroe's constant companion.

The story of Maf the dog is a hilarious and highly original peek into the life of a complex canine hero - he was very much a real historical figure, with his license and photographs sold at auction along with Marilyn's other person affects. Through the eyes of Maf we're provided with an insight into the life of Monroe herself, and a fascinating take on one of the most extraordinary periods of the twentieth century.