The first clip from director Robert Rodriguez’s sequel Machete Kills has landed online, and it’s fittingly ridiculous.  The film centers on Machete’s (Danny Trejo) quest to stop an eccentric billionaire arms dealer who has plans to spread war and anarchy across the planet.  In this clip, we see a car chase between Trejo’s Machete and a car full of angry women, including Sofia Vergara, Alex Vega, and Lady Gaga.  The clip not only shows a gun-wielding, cigarette-toting Lady Gaga crash hard, but we also see Vergara go after Machete with a couple of interestingly placed weapons.

Hit the jump to watch the clip.  The film also stars Mel Gibson,  Michelle Rodriguez, Amber Heard, Charlie Sheen, Jessica Alba, Demian Bichir, Vanessa Hudgens, William Sadler, and Marko Zaror.  Machete Kills will open Fantastic Fest 2013, and opens in wide release on October 11th. [Update: Open Road Films has asked us to remove the clip as it has not officially be approved for release yet.]

Here’s the official synopsis for Machete Kills:

In MACHETE KILLS, Danny Trejo returns as ex-Federale agent MACHETE, who is recruited by the President of the United States for a mission which would be impossible for any mortal man – he must take down a madman revolutionary and an eccentric billionaire arms dealer who has hatched a plan to spread war and anarchy across the planet.