Dean Parisot’s (Galaxy Quest) action-comedy sequel Red 2 opens this weekend.  The follow-up pits ex-CIA operative Frank Moses (Bruce Willis) against Victoria (Helen Mirren) when MI6 greenlights his assassination as Interpol’s “Most Wanted.”  All the while, Moses and his team must work to track down a missing nuclear device.  For more on the film, watch these six clips and the trailer.  Red 2 also stars John Malkovich, Mary-Louise Parker, Catherine Zeta-Jones, Byung Hun Lee, and Anthony Hopkins.

At the recent New York City press junket, I landed an exclusive video interview with Mary-Louise Parker.  She talked about the success of the first film and getting to make the sequel, whether she was excited to finally get in on the action, how things changed on set, and her collection of nude portraits.  Hit the jump to watch.

And if you missed my video interview with Bruce Willis and Anthony Hopkins, click here.

Mary-Louise Parker:

• What does she collect?  Talks about her collection of nude photos and how she has a room full of nudes.
• Was she surprised about the success of the first film and getting to do a sequel
• Was it a fun shoot
• Was she excited to finally get in on the action
• Did they stick to the script or did they discover some of the movie while filming