The dark comedy thriller Better Living Through Chemistry has been going through some casting changes as of late. Last month, Sam Rockwell replaced Jeremy Renner in the lead role (since Renner is starring in every movie possible for the next two years), and now Olivia Wilde is in talks to replace Jennifer Garner in the lead female role. Garner is forced to leave the project not because of scheduling issues, but because she’s now expecting her third child with husband Ben Affleck.Variety reports that Wilde is in talks to play a trophy wife with whom Rockwell’s small-town pharmacist strikes up an affair as a result of a loveless marriage. Things take a turn, however, when the two start using hard drugs and begin plotting the murder of Wilde’s husband. Michelle Monaghan will play Rockwell’s wife and Judi Dench is set as the film’s narrator. Writer/directors Geoff Moore and David Posamentier are making their feature film debut with the project, and I must say I’m quite intrigued. The cast is spot-on for the darkly comic story, so I’m definitely looking forward to seeing how this one shapes up.