Universal Pictures and Illumination Entertainment are teaming up to adapt the Japanese manga Pluto into a live-action/CGI hybrid.  Per Deadline, "The series updates characters from the Osamu Tezuka-created Astro Boy and sets the action in a world populated by giant robots and cybernetic citizens."  Wikipedia adds that author Naoki Urasawa, "reinterprets the story as a suspenseful murder mystery starring Gesicht, a Europol robot detective trying to solve the case of a string of robot and human deaths."  So even if you're not a fan or not familiar with Astro Boy, Pluto sounds like it still has an interesting premise.

Universal and Illumination's first collaboration, Despicable Me, was a hit.  Their next film is the live-action/CG hybrid Hop which stars Russell Brand as the voice of the Easter Bunny and is due out April 2, 2011.  The studios are also developing an adaptation of Dr Seuss' The Lorax, Ricky Gervais' Flanimals, a stop-motion version of The Addams Family directed by Tim Burton, and a sequel to Despicable Me.