Opening in theaters next week is writer/director Leslye Headland’s (Bachelorette) delightfully filthy romantic comedy Sleeping with Other People, and we here at Collider are happy to debut an exclusive clip from the film. Aptly described as “When Harry Met Sally with assholes,” Jason Sudeikis and Alison Brie play two people who, after losing their virginity to each other in college, cross paths years later during a sex addicts meeting in New York City. The subsequently rekindle their friendship on the condition that they won’t sleep with each other, but as they find themselves growing closer as friends, their feelings for one another become more complicated.

This new clip comes from a scene towards the beginning of the film where Sudeikis and Brie’s characters have only just run into each other once again. It’s a solid indicator of the movie’s sense of humor, which is dirty underlined with a hint of sweetness. This clip also features a good look at two of the movie’s secret weapons: co-stars Jason Mantzoukas and Andrea Savage.

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Watch the clip below, click here to read my review from Sundance, and click here for Steve’s video interview with Sudeikis and Headland. Sleeping with Other People opens in theaters on September 11th and also stars Adam Scott, Amanda Peet, Natasha Lyonne, and Adam Brody.

Here’s the official synopsis for Sleeping with Other People:

Years after impulsively losing their virginity to each other in college, Lainey (Alison Brie) and Jake (Jason Sudeikis) meet at a support group in New York (“What’s a nice girl like you doing at a sex addicts meeting?”). A spark resurfaces, but they’ve walked this road before. Abject failures in romance who lead lives of serial infidelity and self-sabotage, they agree to a platonic friendship to mutually support their recovery—and what’s more supportive than teaching your friend proper self-stimulation? Can love bloom while you’re sleeping with other people?