Wayne McClammy, the director of the hilarious Sarah Silverman and Jimmy Kimmel shorts “I’m Fucking Matt Damon” and “I’m Fucking Ben Affleck,” is in negotiations with Universal to direct their upcoming comedy Desperados.  According to The Hollywood Reporter, Isla Fisher may star in the project, which is currently in development.  Mark Gordon and Jason Blum will produce the film written by Ellen Rapaport which is described as a “female version of The Hangover.”  The film is about a woman who sends her new boyfriend an angry email when he doesn’t contact her after they have sex, but it turns out he’s in a coma in a hospital in Mexico so she and her friends go to erase the email before he wakes up.  Production is set to start by the end of the year.

Hit the jump to check out "I'm Fucking Matt Damon" and "I'm Fucking Ben Affleck".

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